Cocaine: Cocaine and crack abuse and distribution pose a significant threat throughout the state of Maryland, particularly in cities situated near Washington, DC. Law enforcement sources in cities and towns located along the Eastern Shore and in western Maryland also cite crack cocaine as the primary drug threat in their areas. Violence continues to accompany the cocaine trade in the state. Wholesale levels of cocaine are readily available via suppliers in New York City and the southwestern U.S.

Heroin: Heroin is abused throughout Maryland but is most problematic in and around the city of Baltimore. Baltimore boasts higher numbers of heroin addicts and heroin-related crime than almost any other city in the nation, and those problems tend to spill over into adjoining counties where many heroin distributors maintain residences. The enormous demand for heroin in the Baltimore metropolitan area led to an increase in the drug's abuse among teens and young adults, who routinely drive into the city to obtain heroin for themselves and other local abusers. In the Baltimore metropolitan area, heroin is sold almost exclusively by street name and packaged in gelatin capsules. Highly pure heroin - "raw" - marketed toward suburban users is sometimes packaged in vials (much like crack cocaine).

Methamphetamine: Methamphetamine is not in high demand nor is it widely available in the state of Maryland. Although clandestine methamphetamine laboratories have been seized in the state in the past few years - one of which was large enough to receive classification by EPIC as a "super-lab" - the problem overall is minimal. Drug users in western Maryland, near West Virginia, and young adults involved in the cities' rave scenes are the primary audiences for methamphetamine.

Club Drugs: Baltimore, Maryland maintains a thriving rave and nightclub scene in which club drugs, usually MDMA, are abused. Club drugs such as Ketamine, GHB and others do not carry the same demand nor availability as MDMA. Notable, however, are recent statements by law enforcement sources that MDMA has become a drug of choice among young, inner-city drug dealers in Baltimore and among young, primarily blue-collar individuals in the western part of the state. A sizeable PCP laboratory was recently seized in the city of Baltimore.

Marijuana:The most widely-abused drug in Maryland, marijuana remains easily available in every part of the state. Low levels of marijuana cultivation occur in the state, primarily in western Maryland and along the Eastern Shore, where private farmland and public parkland are conducive to growers' concerns for anonymity.

OxyContin and Other Prescription Drug Diversion:Until recently, Maryland experienced high levels of pharmaceutical diversion primarily in association with Baltimore's open-air drug markets. OxyContin, however, has become the drug of choice among pharmaceutical drug abusers. Maryland - particularly the city of Baltimore - is becoming a source area for OxyContin abusers in Virginia and West Virginia, likely due to the enormous scrutiny the drug is under in those two states.

Other Drugs: OxyContin and Other Prescription Drug Diversion: Until recently, Maryland experienced high levels of pharmaceutical diversion primarily in association with Baltimore’s open-air drug markets. OxyContin, however, has become the drug of choice among pharmaceutical drug abusers. Maryland – particularly the city of Baltimore – is becoming a source area for OxyContin abusers in Virginia and West Virginia, likely due to the enormous scrutiny the drug is under in those two states.